lucosamine for the Management of
Osteoarthritis
Osteoarthritis commonly occurs in the
weight bearing joints in the body. It also affects the fingers,
thumb, and large toe. The condition causes the joint to lose its
elasticity and become stiff. Over time, the cartilage may slowly wear
away and if the condition worsens, the bones could rub against each
other.
The symptoms of osteoarthritis often
develop slowly. The joint may hurt during movement and the joint may
feel tender when light pressure is applied to it. Joint stiffness may
also be most noticeable after a period of inactivity or when you wake
up in the morning. There is also a considerable decrease in the
ability to move the joints through its full range of motion. Other
patients with osteoarthritis may feel a grating sensation when moving
the affected joint.
Certain factors can increase the risk
of developing osteoarthritis. Women are most likely to develop the
condition. The risk of osteoarthritis also increases with age. Other
factors are bone deformities, previous joint injuries, obesity, and
repetitive stress on the joint.
Osteoarthritis is mostly treated with
analgesics and nonsteroidal anti-inflammatory drugs. However, with
long-term use, these drugs can cause adverse effects, particularly
gastrointestinal and cardiovascular. Thus, disease modifying
alternatives would be best. For the past years, glucosamine has been
increasingly recommended to modify the course of the condition.
People with osteoarthritis who take glucosamine may benefit from
reduced pain and improved physical function.
What is glucosamine?
Glucosamine is a natural compound that
is found in healthy cartilage. It is naturally produced in the body
and plays a key role in building cartilage. It is an amino sugar that
the body produces and distributes in cartilage and other connective
tissue.
Several scientific studies have
suggested the effectiveness of glucosamine in the treatment of
osteoarthritis. The results suggest the glucosamine supplements may
help reduce osteoarthritis pain. It is also helpful in reducing joint
swelling and stiffness. Studies have shown that it helps improve
joint mobility.
Since the natural glucosamine in the
body is used to make and repair joint cartilage, glucosamine in the
form of nutritional supplements are used in the management of
osteoarthritis by helping repair damaged cartilage.
There are no major food sources of
glucosamine. Oral supplements are available as glucosamine sulfate,
glucosamine hydrochloride, and n-acetyl glucosamine.
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